Step into the shoes of The Preacher, one of the last remaining members of the infamous Abrams Family Cult, a massive group of religious vampire-hunters led by their Father Prophet, Gregory Abrams--a man who believed he had a direct connection to God and who's crusade against all Vampire kind ultimately led to his and his followers demise. Sixteen years after the Cult was massacred, Abrams, joined by their Hunting Partner and Mentor, Wyatt Abrams have survived the best they can--the only way they know how--together.

Things seem to be business as usual for the two of them, scheming by day, vampire hunting by night until it's found out that someone's taken a hit out on both of their heads--forcing them to seek refuge in the small town of Larkin, Nevada, where the title of town Preacher is unexpectedly thrust upon Abrams.

As if dealing with the complicated history that lies with Abrams' relationship with religion wasn't enough, on their first day in town the local silver mine explodes, and Wyatt and Abrams are left as the main suspects. Forced to solve the mystery of the mining accident, Abrams must navigate their way through a town with many hidden secrets--including a ruling coven of vampires, an Abrams reformist cult and a gang of outlaws determined to wage war on Larkin.